Like Mo Farah and Jessica Ennis-Hill, the British stars of the two-day Anniversary Games, Bolt will be hoping to find the Midas touch that took him to Olympic gold on the same east London track in 2012.
The 28-year-old Jamaican last raced on June 13, when he struggled to get the better of his 19-year-old training partner, the Anguillan-born British recruit Zharnel Hughes, over 200m in the New York Diamond League meeting.
With American Justin Gatlin a clear leader of the world rankings at both 100m (9.74 seconds) and 200m (19.57sec), Bolt desperately needs to rediscover a measure of the form that took him to his second set of Olympic 100m, 200m and 4 x 100m relay golds three years ago.
Bolt, the 100m and 200m world record holder and reigning world champion, has been reported in the Jamaican press to have been "going well" at his European training base at Brunel University in west London but he faces not one but two tests on his comeback, with heats on the schedule at the Olympic Stadium.
