After analysing 10 years of medical tests on more than 2,700 people, researchers at Johns Hopkins University School of Medicine in the US, said the results add to growing scientific concerns about the potential harms of supplement.
"Our study adds to the body of evidence that excess calcium in the form of supplements may harm the heart and vascular system," said Erin Michos, from Johns Hopkins Medicine.
Scientists also knew that as a person ages, calcium-based plaque builds up in the body's main blood vessel, the aorta and other arteries, impeding blood flow and increasing the risk of heart attack.
The researchers looked at detailed information from the Multi-Ethnic Study of Atherosclerosis, a long-running research project which included more than 6,000 people.
At the study's onset in 2000, all participants answered a 120-part questionnaire about their dietary habits to determine how much calcium they took in by eating dairy products, leafy greens and calcium-enriched foods such as cereals.
For the analysis, the researchers first split the participants into five groups based on their total calcium intake, including both calcium supplements and dietary calcium.
of calcium a day.
That group was found to be on average 27 per cent less likely than the 20 per cent of participants with the lowest calcium intake - less than 400 milligrammes of daily calcium - to develop heart disease, as indicated by their coronary artery calcium test.
The research was published in the Journal of the American Heart Association.
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