Amid an epidemic of addiction and abuse tied to these powerful opioids drugs, the Centers for Disease Control and Prevention is urging primary care doctors to try physical therapy, exercise and over-the-counter pain medications before turning to painkillers for chronic pain.
Opioid drugs include medications like morphine and oxycodone as well as illegal narcotics like heroin.
The new recommendations - which doctors do not have to follow - represent an effort to reverse nearly two decades of rising painkiller use, which public health officials blame for a more than four-fold increase in overdose deaths tied to the drugs.
"We're trying to chart a safer and more effective course for dealing with chronic pain," Dr. Tom Frieden, the CDC's director, said in an interview with the Associated Press.
"The risks of addiction and death are very well documented for these medications."
More than 40 Americans die every day from painkiller overdoses, a staggering rate that Frieden said is "doctor driven."
Under the new guidelines, doctors would prescribe painkillers only after considering non-addictive pain relievers, behavioural changes and other options.
And doctors should only continue prescribing the drugs if patients show significant improvement.
For short-term pain, the CDC recommends limiting opioids to three days of treatment, when possible.
The guidelines do not apply to doctors who specialize in treating severe pain due to cancer and other debilitating diseases.
Though the guidelines are voluntary, they could be widely adopted by hospitals, insurers and state and federal health systems.
Government officials have already tried multiple approaches to tackling painkiller abuse.
The Food and Drug Administration restricted some widely-prescribed painkillers to limit refills.
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