The result heralds the start of an epic race to the White House between Clinton, 68, and brash real estate tycoon Trump who celebrated his 70th birthday today.
Clinton, a former Secretary of State and a former Senator from New York, is the first women to become a presidential candidate of a major political party in US electoral history.
"We just won Washington, DC ! Grateful to everyone who voted," Clinton tweeted though Sanders is yet to drop out of the race as the two met today.
Clinton also received support from 581 super delegates - who are primarily the party's office bearers and elected officials - as against just 49 for Sanders.
In total Clinton now has 2800 delegates out of 4763 delegates. The half way mark is 2382. Sanders has 1832 delegates in his kitty.
Ending the primary elections on a winning note puts the former first lady on a sound footing ahead of the general election in November and the Democratic Party's convention in Philadelphia in July.
"Now that our 2016 primaries are officially at their end, Democrats are ready to unify and take on both Trump and the Republican Party that he represents. At our convention in July, we're going to nominate a qualified, capable candidate who will build on the hard-won progress of the last seven years," she said.
Nearly 28 million people cast their ballots for Clinton and Sanders in Democratic primaries - 2.7 million more than the top three Republican candidates combined.
Vermont Senator had a positive discussion with Clinton about how best to bring more people into the political process and about the "dangerous" threat that Trump poses to the US.
"Sanders congratulated Secretary Clinton on the campaign she has run and said he appreciated her strong commitment to stopping Trump in the general election," it said.
It added that the two discussed a variety of issues where they are seeking common ground: substantially raising minimum wage; real campaign finance reform; making health care universal and accessible and making college affordable and reducing student debt.
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