The coordinated operation was announced yesterday as the US Treasury Department froze US assets owned by 68 companies in this Central American nation and in Colombia under a drug kingpin designation.
As part of the effort, Colombian police arrested Nidal Waked the previous day at an airport in Colombia's capital, Bogota.
The Colombian police today showed reporters several videos of Waked taken after his arrest. In one, he is reading the charges against him and a list of rights for prisoners held in Colombia.
The family also owns Panama's oldest newspaper, the Estrella de Panama.
Grupo Wisa, the family's holding company, issued a terse statement saying the accusations "are false and unfounded." The company said it had instructed its lawyers to cooperate fully in the investigation announced by Panama's attorney general.
The action comes as Panama is struggling to overcome international rebuke of its offshore banking system in the wake of a damaging leak of 11.5 million documents detailing how a prominent law firm helped the world's rich and famous hide their wealth.
The Drug Enforcement Administration described Waked as "one of the world's most significant drug money launderers and criminal facilitators." It said he faces money laundering and bank fraud charges in Florida.
A law enforcement official, who agreed to discuss the matter only if not quoted by name because he was not authorized to discuss the case publicly, said the Waked family is accused of laundering funds on behalf of Colombian and Mexican drug cartels as well as independent drug-trafficking organisations.
