The recipient of the letter, Julius Frazelle Galbraith of Nelsonville, Manitoba in Canada, had written a three-page long letter to Darwin on October 20, 1881.
Galbraith recounts an incident of development of worms in a barrel of wheat, noting that he had pondered Darwin's view that plants and animals may have had a common ancestor.
In a reply dated November 11, 1881, Darwin tactfully sets him straight, according to Boston-based RR Auctions
"There was plenty of time and means for the indefinite multiplication of innumerable kinds of animals in the cask," he wrote.
Signed "Ch. Darwin" the one-page letter is in good condition, with light soiling and staining, the auction said.
The bidding for the letter ends on March 7.
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