In the first visit by a US defence secretary in nearly four years, Hagel will fly from Kabul to Islamabad to meet Prime Minister Nawaz Sharif and other top officials, including the country's new army chief.
Ties between Washington and Islamabad have been seriously strained over US drone strikes in Pakistan's tribal belt as well as Afghan Taliban sanctuaries inside Pakistan's borders.
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The visit was announced as Hagel's deputies said NATO shipments out of Afghanistan through Pakistan would resume after the end of anti-drone protests.
In recent weeks, activists opposed to the drone raids forcibly searched trucks in northwest Pakistan in a campaign to disrupt NATO supply routes to and from Afghanistan.
The club-wielding protesters prompted US officials to temporarily halt the shipments to protect the safety of truck drivers ferrying NATO equipment.
But a US defence official told reporters in Kabul that the suspension of shipments via Pakistan had been lifted because the protests had stopped, removing the threat to NATO trucks that move through the Torkham gate pass.
The crossing is the main overland route used by the Americans and NATO to withdraw tonnes of military hardware from Afghanistan as part of a massive troop pullout set to wrap up by the end of 2014.
President Barack Obama has defended the drone strikes as an effective, lawful tool used with restraint to target suspected Al-Qaeda militants. But human rights groups and Pakistani politicians say the missile attacks have killed innocent civilians and must stop.
As part of his brief visit to Islamabad, Hagel was expected to meet the country's newly appointed army chief, General Raheel Sharif.
The position holds special significance in Pakistan and US officials are anxious to forge a constructive dialogue with a figure expected to be at the centre of decision making on sensitive security questions.
The veteran infantry commander last month succeeded General Ashfaq Kayani, who is retiring after six years at the helm.
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