Using data from 10 independent clinical trials with a total of 385 patients with schizophrenia, researchers at University of Manchester in the UK found that around 12 weeks of aerobic exercise training can significant improve patients' brain functioning.
Schizophrenia's acute phase is typified by hallucinations and delusions, which are usually treatable with medication.
However, most patients are still troubled with pervasive 'cognitive deficits'; including poor memory, impaired information processing and loss of concentration.
The research showed that patients who are treated with aerobic exercise programmes, such as treadmills and exercise bikes, in combination with their medication, will improve their overall brain functioning more than those treated with medications alone.
There was also evidence among the studies that programs which used greater amounts of exercise, and those which were most successful for improving fitness, had the greatest effects on cognitive functioning.
"Cognitive deficits are one aspect of schizophrenia which is particularly problematic," said Joseph Firth.
"They hinder recovery and impact negatively upon people's ability to function in work and social situations. Furthermore, current medications for schizophrenia do not treat the cognitive deficits of the disorder," said Firth.
"Using exercise from the earliest stages of the illness could reduce the likelihood of long-term disability, and facilitate full, functional recovery for patients," Firth said.
The study was published in the journal Schizophrenia Bulletin.
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