"Of course, he is dismayed about the death of Garcia Marquez, who was his dear friend," Vice President Miguel Diaz-Canel told reporters.
It was the first official reaction from the 87-year-old Castro following the death of the Nobel-winning Colombian author in Mexico City last week.
The pair met after Castro grabbed power in the 1959 revolution. Garcia Marquez had come to Cuba as a journalist to cover Castro's band of guerrillas.
"Fidel is a man of great human sensitivity," Diaz-Canel told reporters at the Colombian embassy in Havana, where he had gone to sign a book of condolences.
"He feels the loss of a friend -- like anyone who has human sensibilities would."
Diaz-Canel also spoke briefly about Castro's health, saying it was "very good" and adding, "He is working intensely on various things that have occupied his time recently.
