If the theory, that the remains belonged to the first such known hybrid, is proven correct, it will provide direct evidence that humans and Neanderthals interbred.
Previous genetic studies have determined the DNA of people with European and Asian ancestry to be 1 to 4 per cent Neanderthal, 'Discovery News' reported.
In the present study, the researchers focused on the individual's jaw, which was unearthed at a rock-shelter called in the Monti Lessini region of Italy. Both Neanderthals and modern humans inhabited Europe at the time.
Researchers led by Condemi studied the remains using DNA analysis and 3D imaging and then compared those results with the same features from humans.
Interestingly, the genetic analysis found that the individual's mitochondrial DNA is Neanderthal.
Since this DNA is transmitted from a mother to her child, the researchers concluded that it was a "female Neanderthal who mated with male Homo sapiens."
It suggests that the two populations did not simply meet, mate and merge into a single group.
Previous fossil studies have indicated that modern humans were living in a southern Italy cave as early as 45,000 years ago, the report said.
Neanderthal culture and purebred Neanderthals all died out 35,000-30,000 years ago.
The study was published in the journal PLoS ONE.
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