The quartet - who play Brittany, Puck, Mercedes and Mike respectively - may return as occasional guest stars but will no longer have major roles in the show, according to E! online.
Dianna Agron (Quinn) is also set to leave the show, after the actress only appeared in a few episodes in season four.
Meanwhile, Chris Colfer - who stars as openly gay teenager
Kurt Hummel in the hit musical - has no plans to leave the show in the near future and hopes there are more interesting storylines to come for Kurt.
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