Two of the female tourists suffered facial injuries during the late morning attack at Marseille's Saint Charles train station and one of the two also had a possible eye injury, a spokeswoman for the Marseille prosecutor's office told The Associated Press in a phone call.
She said all four of the women, who are in their 20s, were hospitalized, two of them for shock. The suspect was taken into police custody.
The Paris prosecutor's office said that its counter- terrorism division has decided for the time being not to assume jurisdiction for investigating the attack. The prosecutor's office in the capital, which has responsibility for all terror-related cases in France, did not explain the reasoning behind the decision.
The spokeswoman for the Marseille prosecutor's office said the suspect did not make any extremist threats or declarations during the attack. She said there were no obvious indications that the woman's actions were terror-related.
Two of the Americans were "slightly injured" with acid but did not require emergency medical treatment from medics at the scene, the spokeswoman said. She requested anonymity in keeping with fire department protocol.
Regional newspaper La Provence, quoting unidentified police officials, reported that the suspect had a history of mental health problems and noted that she remained at the site of the attack without trying to flee.
A spokesman for the United States embassy in Paris said the US consulate in Marseille was in contact with French authorities.
Marseille is a port city in southern France that is closer to Barcelona than Paris.
In previous incidents in Marseille, a driver deliberately rammed into two bus stops last month, killing a woman, but officials said it wasn't terror-related.
In April, French police said they thwarted an imminent "terror attack" and arrested two suspected radicals in Marseille just days before the first round of France's presidential election. Paris prosecutor Francois Molins told reporters the two suspects "were getting ready to carry out an imminent, violent action."
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