At the heart of the case is Lagarde's decision to allow a dispute with Bernard Tapie to be resolved by arbitration in 2007 and her later failure to contest the huge award linked to the flamboyant businessman's sale of the Adidas sports brand to the state-owned Credit Lyonnais bank.
Lagarde argued in court on Friday she had acted in good faith in approving the 404-million-euro (USD 422 million) payment to Tapie to settle the row.
The verdict is expected at 1930 IST.
If convicted, Lagarde could face a year in prison and a 15,000 euro fine.
The IMF has so far given Lagarde its full backing in the case, but the organisation would be concerned at any damage to its reputation that a conviction could bring.
Lagarde is being tried by the Court of Justice of the Republic, a tribunal staffed by judges and members of parliament that hears cases against ministers accused of wrongdoing in office.
The prosecutor has made it clear he is opposed to convicting Lagarde, judging the evidence to support the charge of negligence too flimsy.
"The hearings have not backed up a very weak charge," Jean-Claude Marin told the court.
The prosecutor's office had advised against bringing the case to trial.
Lagarde waved through the settlement to Tapie in 2008.
The payout raised concerns given Tapie's vocal support for Lagarde's then boss, ex-president Nicolas Sarkozy, and it was subsequently cancelled by the courts.
Lagarde has told the trial she had trusted the judgement of her subordinates in the process and had not been included in some of the negotiations in the ministry and in the president's office.
As IMF chief Lagarde has been a key player in bailout negotiations for Greece and has also worked to reform the US- and Europe-dominated institution to reflect China's growing global leverage.
Another former IMF head, Rodrigo Rato of Spain, is currently standing trial on charges of misusing funds when he was head of Spanish lender Bankia.
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