With less than three months to go before an informal July deadline, Iranian Foreign Minister Mohamad Javad Zarif said the talks Tuesday and Wednesday in Vienna are meant to start work on drafting the text of an agreement.
Initial rounds in February and March dealt in generalities and work on the text "is the difficult part," he said.
"Probably at the beginning of preparing the draft, the differences will be lots," he told Iran's state-run television.
The US, Britain, France and Germany want significant cuts, to limit the potential for the program to be used for making high-enriched material for nuclear arms. Russia and China are somewhere in the middle.
The six also want to eliminate potential proliferation dangers from an enrichment site at Fordo, south of Tehran, that is built far underground to withstand air strikes; and a nearly built nuclear reactor at Arak, in northwestern Iran, that would produce substantial amounts of plutonium unless it is re-engineered to new specifications.
Zarif said the two sides would "review all the topics" Tuesday and Wednesday but cautioned of tough work ahead.
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