Netanyahu's comments came at the start of a meeting with visiting Dutch Foreign Minister Bert Koenders.
Netanyahu, who had stated that he would relate to the details of the accord at a latter time, said it is the result of wanting to reach an agreement "at any price."
The Prime Minister said that the powers negotiating with Iran -- the US, Russia, China, France, Britain and Germany -- made far reaching concessions on the areas meant to prevent Iran from ever being able to obtain nuclear arms.
"Iran will get a jackpot, a cash bonanza of hundreds of billions of dollars, which will enable it to continue to pursue its aggression and terror in the region and in the world," the Premier said on Israel's arch-foe.
"It is impossible to prevent an agreement when the negotiators are willing to make more and more concessions to those who chant 'Death to America' even during the negotiations," he said.
Led by the United States the so-called P5+1 countries reached the landmark agreement with Iran after more than 20 months of intense negotiations, mostly held in Vienna or Geneva.
Iran will not use its advanced centrifuges to produce enriched uranium for the next decade. Iran will also get rid of 98 per cent of its stockpile of enriched uranium, he said.
Netanyahu said that because the Israeli government knew that the desire to reach an agreement was greater than anything else, it never committed itself to prevent the accord.
Netanyahu, coming under withering criticism from the opposition for what is being termed a colossal failure on his part to stop the agreement, called for Israel's political leaders to put party politics aside and unite around a most fateful issue for Israel's future and security.
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