The vessel, dubbed "Kounotori" (stork in Japanese), is to blast off from the southern island of Tanegashima around 10:30 pm local time attached to an H-IIB rocket.
Scientists at the Japan Aerospace Exploration Agency (JAXA) are experimenting with a tether to pull junk out of orbit around Earth, clearing up tonnes of space clutter including cast-off equipment from old satellites and pieces of rocket.
More than 50 years of human space exploration since the Soviet-launched Sputnik satellite in 1957 has produced this hazardous belt of orbiting debris.
Researchers are using a so-called electrodynamic tether made from thin wires of stainless steel and aluminium.
The idea is that one end of the strip will be attached to debris which can damage working equipment -- there are hundreds of collisions every year.
The electricity generated by the tether as it swings through the Earth's magnetic field is expected to have a slowing effect on the space junk, which should, scientists say, pull it into a lower and lower orbit.
JAXA worked on the project with Japanese fishnet manufacturer Nitto Seimo to develop the cord, which has been about 10 years in the making.
"The tether uses our fishnet plaiting technology, but it was really tough to intertwine the very thin materials," company engineer Katsuya Suzuki told AFP.
"The length of the tether this time is 700 metre (2,300 feet), but eventually it's going to need to be 5,000 to 10,000 metre-long to slow down the targeted space junk," he added.
A spokesman for the space agency said it hopes to put the junk collection system into more regular use by the middle of the next decade.
"If we are successful in this trial, the next step will be another test attaching one tip of the tether to a targeted object," he added.
The cargo ship launched Friday is also carrying other materials for the ISS including batteries and drinking water for the astronauts living there.
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