England striker Kane finishes with 29 league goals, winning the Golden Boot ahead of Everton's Romelu Lukaku and Arsenal's Alexis Sanchez.
Dele Alli, Victor Wanyama, Ben Davies and Toby Alderweireld were also on target for the visitors, who were already guaranteed to finish second to champions Chelsea, while Sam Clucas's second-half strike was a rare highlight for the home fans.
Kane is only the fifth player to win the Premier League's Golden Boot in successive seasons, following Alan Shearer, Michael Owen, Thierry Henry and Robin van Persie.
The 23-year-old added to his impressive tally with two goals in less than three minutes.
The first was a fierce left-foot drive from 20 yards after Christian Eriksen's square pass and the second, two minutes and 39 seconds later, capped a lovely passing move.
Eric Dier's long pass from the halfway line was perfect for Kieran Trippier to cushion into the six-yard box, where Kane was waiting to apply a first-time finish.
Hull fans voiced support for Marco Silva, their popular head coach. "We want you to stay," they sang.
The Portuguese was unable to prevent Hull's relegation but did his burgeoning reputation no harm with his efforts and approach.
Hull were bottom table when Silva arrived in January but the former Olympiacos and Sporting manager gave them hope -- albeit in vain -- with six wins from seven home matches before a damaging defeat by Sunderland earlier this month.
Kane was again involved, threading the ball through to Son Heung-Min. The South Korea international cut the ball back to Alli, who checked on to his right foot and fired his shot low under David Marshall.
It was Alli's 18th Premier League goal of the season.
- Stadium proclaims Kane -
==========================
Silva responded by introducing winger Kamil Grosicki in place of defender Curtis Davies and, while Spurs arguably eased up, Hull improved after the break.
Grosicki was then instrumental as Hull pulled a goal back with 24 minutes remaining. His low cross found Niasse, who after having a shot blocked, rolled the ball back for Clucas to send a deflected shot into the bottom corner.
Spurs restored their advantage as Wanyama -- seemingly from an offside position -- headed in at the back post from Eriksen's free-kick before Kane completed his hat-trick.
Hull were caught in possession in their own half and Spurs were ruthless, as Alli's through ball was finished calmly by Kane, who became the sixth player in Premier League history to score successive hat-tricks.
Hull looked dead on their feet but Spurs kept pushing.
It was six when Davies smashed in a shot from 20 yards after Wanyama's lay-off and seven when Alderweireld finished at the back post from Trippier's cross.
Disclaimer: No Business Standard Journalist was involved in creation of this content
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