The bypoll was necessitated by the resignation of incumbent Kadiam Srihari who became the deputy chief minister of Telangana and the TRS is expected to leave no stone unturned to retain the seat.
Losing the bye-election would be dubbed as a reflection on the performance of Chief Minister K Chandrasekhar Rao's government.
The main opposition Congress would like to salvage its prestige by winning the bypoll following its failure in last year's elections.
Meanwhile, NDA allies TDP and BJP are keen to project themselves as an alternative to the ruling TRS by winning the bypoll.
No party has announced its candidate so far for the bye-election.
More than 14 lakh voters are eligible to exercise their franchise in the by-poll.
