Before heading to Switzerland to try to reach a deal on Iran's nuclear program, Kerry and his top official for Mideast affairs, Anne Patterson, met Moaz al-Khatib, a leading Syrian opposition figure.
The three discussed "ways to advance a political solution to the crisis in Syria," said a statement from State Department spokeswoman Jen Psaki.
"Secretary Kerry emphasized that Bashar al-Assad is a brutal dictator with no legitimacy to lead Syria," Psaki added.
The United States has said that a transition could take place with elements of the current regime in Syria, but not Assad himself, and has consistently called for him to step down.
But on March 15, Kerry appeared to suggest in a CBS television interview that Washington would have to talk with Assad eventually if peace was to be forged.
Psaki later clarified that Kerry was referring to representatives of the Assad regime, and not Bashar al-Assad himself.
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