The 25-year-old Railways girl, who had the previous best of 16.39 at last year's Delhi National Open, threw the iron ball to 17.96m in her second attempt to shatter Harbans Kaur's earlier national record of 17.43m that stood since 1997.
This was Manpreet's hat-trick of gold medals at the National Open and sixth overall as she also got past the Olympics qualification mark of 17.80m.
Jaisha clocked 15:31.73 to better Preeja Sreedharan's eight-year old meet record of 15:45.96 as Railways made a clean sweep in the women's 5000m.
Sarita Singh bagged Railways the third gold of the day when she threw 58.97m in the hammer throw, while Sonam of LIC and Gunjan Singh of Railways bagged silver and bronze respectively.
The day also marked the return of Odisha sprinter Dutee Chand who represented Railways as she blazed the track in the 100m dash semifinals.
But the Court of Arbitration for Sport, in its July verdict, suspended the "hyperandrogenism" rules, which will be scrapped if the IAAF, the world body of the sport, cannot provide new evidence.
