Keegan, 26, bested the likes of Jorgie Porter, Katrina Bowden, Olivia Munn and Emily Atack in the poll for FHM magazine, reported OK! magazine.
Keegan, who got engaged to actor Mark Wright last month, celebrated her win by stripping down to her underwear.
"I really didn't expect that! It's very flattering, especially as I don't play anyone sexy. My character, Tina, is really dressed down and she's a tomboy, so I don't really get it, but I'm chuffed!
"I agree that girls look better when they're dressed more natural. I think that's a bit more, not sexy, but real, you know? And I find that more attractive. You know what it is? I think you're more sexy when you're not trying," she said.
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