The explosion happened late yesterday in Escambia County jail's booking facility and caused the building to partially collapse, said Kathleen Castro, the county's public information manager.
About 600 inmates were in the building at the time, she said.
Castro didn't know if flooding in the area was a factor but says the jail did get extensive flooding during heavy rains that have drenched the region on Tuesday and yesterday.
The injured were brought to hospitals and the uninjured inmates were brought to jails in neighbouring counties, Castro said.
Vicki Brooks, a spokeswoman for Sacred Heart, said they treated 31 patients with mostly neck and back injuries.
Kendrick Doidge said West Florida Hospital treated 37 inmates in the emergency room and all have been released back into the custody of the Escambia County Sheriff's Office.
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