New wireless patch may ease migraine pain without drugs

A new, smartphone controlled wireless patch that can be worn on the arm may help reduce migraine pain as effectively as drugs, a new study claims.
The device uses electrical stimulation to block the pain signals from reaching the brain. The patch uses rubber electrodes and a chip on an armband.
The patch can be controlled by a smartphone app. In the past when stimulation has been tested for people with migraine, devices needed wires and were attached to the head.
"These results need to be confirmed with additional studies, but they are exciting," said study author David Yarnitsky, of Technion Faculty of Medicine in Israel.

"People with migraine are looking for non-drug treatments, and this new device is easy to use, has no side effects and can be conveniently used in work or social settings," said Yarnitsky.
The study involved 71 people with episodic migraine who had two to eight attacks per month and had not taken any preventive medication for migraine for at least two months.

Participants were asked to apply the device to their upper arm soon after the start of a migraine and use it for 20 minutes. They were not supposed to take any medications for migraine for two hours.
The devices were programmed to randomly give either a placebo, or sham, stimulation at a very low frequency or one of four levels of active stimulation. The stimulation was designed to not be painful.

A total of 299 migraines were treated with the device during the study.
During the active stimulation at the three highest levels, 64 per cent of people had a reduction in their pain by at least 50 per cent two hours after the treatment, compared to 26 per cent of people during the sham stimulation.
For those who started with moderate to severe pain, their pain was reduced to mild or no pain in 58 per cent of people at the highest level of stimulation, compared to 24 per cent of those during the sham stimulation, the study found.
In the same group, 30 per cent said they had no pain after receiving the highest level of stimulation, compared to six per cent of those receiving the sham stimulation.

"These results are similar to those seen for the triptan medications for migraine," said Yarnitsky.
The researchers also found that starting the stimulation within 20 minutes of the start of a migraine was more effective, with 47 per cent reducing pain when starting early, compared to 25 per cent who started after 20 minutes.
The study was published in the journal Neurology.