Overseas, most European stocks were trading mixed after the Federal Reserve raised interest rates for the first time in a year and as investors eyed the Bank of England's monetary policy decision due later.
Asian stock markets edged lower as dollar strengthened sharply and investors digest the Federal Reserve's first interest rate rise this year.
Back home, the Nifty opened lower at 8,128.40 and moved in a range of 8,225.90 and 8,121.95 before ending at 8,153.60, showing a fall of 28.85 pts or 0.35 per cent.
On sectoral front, Pharma fell by 1.88 per cent, FMCG (0.87 per cent), Media (0.63 per cent), Energy (0.39 percent), Infra (0.31 per cent) and Auto (0.30 per cent).
However, PSU Bank rose by 0.75 per cent followed by IT 0.66 per cent, Bank 0.33 per cent, Pvt. Bank 0.24 per cent and realty 0.24 per cent.
Major index laggards were ONGC (32.38 per cent), Sun Pharma (4.19 per cent), TataMtrDvr (2.74 per cent), Grasim (2.29 per cent), NTPC (2.05 per cent) and Tata Motors (1.94 per cent).
The gainers included TCS (2.34 per cent), Axis Bank (2.33 per cent), HCL Tech (1.38 per cent), M&M (1.07 per cent) Bank of Baroda (0.98 per cent).
Turnover in the cash segment rose to 17,108.61 crore from Rs 16,150.98 crore as on Wednesday.
A total of 7,960.17 lakh shares changed hands in 7,486,692 trades. The market capitalisation of NSE stood at Rs 10,489,815.20 crore.
Disclaimer: No Business Standard Journalist was involved in creation of this content
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