Nifty Metal, PSU Bank, Infra, Energy, Pharma and Finance Service indices fell the most on the back of bearish global cues.
Overseas, European stocks were trading lower as Banca Monte dei Paschi di Siena SpA's eleventh-hour bid to raise capital looked set to fail, dragging bank shares lower.
Asian stocks suffered modest losses after an overnight lacklustre performance on Wall Street, with investors awaiting US economic data later in the day for potential catalysts even as markets started winding down ahead of the holidays.
It saw an intra-day movement of about 81.50 points.
On the sectoral front, Metal fell 2.85 per cent, followed by PSU Bank (1.90 per cent), Infra (1.88 per cent), Energy (1.33 per cent), Pharma (1.31 percent), Finance Service (1.19 per cent), Bank (1.07 per cent), Pvt Bank (0.96 per cent), IT (0.64 per cent) and Realty (0.51 per cent).
Major index laggards were Hindalco (4.47 per cent), Adani Ports (3.88 per cent), ONGC (3.28 per cent), Bharti Airtel (3.13 per cent) and Tata Steel (3.04 pct).
A total of 1,329 scrips declined 291 advanced while 56 remained unchanged. Total securities that hit their price bands were 99.
Turnover in the cash segment fell to Rs 13,533.63 crore from Rs 14,048.65 crore as on Wednesday.
A total of 6,763.35 lakh shares changed hands in 6,385,308 trades. The market capitalisation of NSE stood at Rs 10,218,359.34 crore.
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