At least three student activists had to be taken to a hospital after they were run over by the van driven by a police officer, protest leader Renato Reyes said.
AP Television footage showed the van repeatedly ramming the protesters as it drove wildly back and forth after protesters had surrounded and started hitting the van with wooden batons they had seized from the police.
Police later arrested 23 protesters, who broke into a line of riot police and hurled red paint at the policemen and a US government seal at the seaside embassy.
The violence happened as the protesters gathered to demand an end to the presence of US troops in the country and to support a call by President Rodrigo Duterte for a foreign policy not dependent on the US, the country's longtime treaty ally.
Duterte was on a state visit to China, where he is seeking to repair relations strained under his predecessor over territorial conflicts in the South China Sea. Duterte is also seeking to expand two-way trade and investments and seek financing for badly needed infrastructure projects.
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