US Secretary of State John Kerry and his Iranian counterpart Mohammad Javad Zarif talked through the night, going line by line over their differences in a bid to seal the outlines of a framework accord to cut back Iran's nuclear ambitions, diplomats close to the talks said.
They made "significant progress," but there is no "final result yet," Zarif told reporters at the luxury lakeside Lausanne hotel hosting the marathon negotiations for the past eight days.
But a Western diplomat cautioned "the conclusion is far from being imminent."
And German Foreign Minister Frank-Walter Steinmeier cancelled a planned trip to the Baltics to stay at the talks in Switzerland.
In a sign that eight days of negotiations may be drawing to a close, Zarif said he and EU foreign policy chief Federica Mogherini would make a "joint declaration" to the press if everyone was in agreement.
"But the text still has to be worked on," he said.
The aim is to turn this into a comprehensive accord backed by specific technical commitments by June 30 when an interim deal struck in November 2013 expires.
After just a few hours sleep, the six world powers -- Britain, China, France, Germany, Russia and the United States -- were back at the negotiating table.
The stakes were very high, French Foreign Minister Laurent Fabius said, adding that at issue was the question of non- proliferation, and "Iran's reintegration into the international community."
Success in Lausanne would end a 12-year-old standoff. Failure may set the United States and Israel on a road to military action to thwart Iran's nuclear drive.
The White House said the talks were still "productive" and progress was being made.
"But if we are in a situation where we sense that the talks have stalled then yes, the United States and the international community is prepared to walk away," said White House spokesman Josh Earnest.
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