"We hope this latest development leads to an outcome that reflects the fact that bringing Osama bin Laden to justice was clearly in Pakistan's interests as well as ours," said State Department Deputy Spokesperson Marie Harf.
"We continue to believe, of course, that the prosecution and conviction of Dr Afridi sends exactly the wrong message about the importance of this shared interest," Harf told reporters.
Harf said she would not use the words welcome or pleased for the latest developments in Afridi's case.
"We have seen the reports that Dr Afridi's sentence was overturned. Our position on Dr Afridi has long been clear. We regret both that he was convicted and the severity of his sentence," she said.
"We hope this latest development leads to an outcome that reflects the fact that we believe this was in both of our shared interests. I know there's a process, and I just don't want to get ahead of it," Harf said.
"This heroic doctor should never have been charged with a crime in the first place. This at least gives Pakistan a chance to redeem itself," he said.
"Hopefully Pakistan will take a second look and totally free Dr Afridi. Until then, Congress must assume that Pakistan has a government hostile to the United States."
Rohrabacher applauded diplomatic efforts and the hard work and commitment of American citizens who had stood up for Afridi, who helped bring to justice the terrorist mastermind behind 9/11.
Bin Laden was killed in 2011 in an unilateral US military raid in Abbottabad, where Afridi ran a fake vaccination campaign to help the CIA track the Al Qaeda chief.
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