Pai blasted the activists for "harassing" his family members, saying they "crossed the line".
Pai is facing backlash from his opponents for his proposal which seeks to reverse Obama era's net neutrality, which meant that all websites are treated equally by Internet providers.
His proposal would end net neutrality and give big Internet providers like Comcast and Verizon broad powers to determine what website should reach out to subscribers faster than others.
Some media reports said the frequency was every 15 minutes.
This is the first instance that a senior Indian-American administration official in any of the presidential administration being harassed and threatened by opponents not agreeing to his views.
Signboards and placards placed by protestors outside Pai's house in Virginia mocked him for his views.
"Is this really the world you want Annabelle and Alexander to inherit? How will they ever look you in the eye again," was written in one of the posters.
You do not have to be evil," written in another poster.
In an interview to Fox and Friends, Pai said that his opponents have "crossed the line".
"I understand that people are passionate about policy, but the one thing in America that should remain sacred is that families, wives and kids, should remain out of it. And stop harassing us at our homes," Pai told Fox and Friends.
Pai's proposal is scheduled to come out to vote before FCC on December 14.
Pai expressed his displeasure when asked about the protest outside his house in Virginia.
"It was a little nerve-racking, especially for my wife," he said.
"Internet regulation activists have crossed the line by threatening and harassing my family. They should leave my family out of this and focus on debating the merits of the issue," Pai said in a statement reported by The Washington Post.
"That's one of the things I think is very unfortunate about all the vitriol and hot air that's out there is that if you keep going out there and peddling this misinformation like 'this is the guy who is going to break the Internet and destroy democracy', it's not surprising that some people get alarmed by it," he said.
Instead, he argued, "companies should be transparent about their policies".
Free Press Action, which has been seeking net neutrality condemned the personal attack against Pai and his family.
"If you are sending racist message to FCC Chairman Ajit Pai, mocking his name, heritage or family, we do not want you in this new neutrality fight," it said.
According to Brendan Bordelon, a cybers ecurity reporter at National Journal, "Pizzas also reportedly set to his house every half-hour last night," he said, adding that "the racist memes and the hyperbolic social media attacks are bad enough. This is deeply disturbing".
Disclaimer: No Business Standard Journalist was involved in creation of this content
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