According to TMZ, the rapper born Derrick Coleman suffered a fatal seizure on Friday night in Los Angeles.
Santana was hospitalised recently for longstanding liver and kidney problems.
He frequently spoke about using lean, which includes codeine and contributed to the 2007 death of influential Houston rapper Pimp C.
Several rappers, including Drake paid tribute to Santana.
Lil B posted, "Let one off in the air for fredo santana !! For life they couldn't stop that man SSR for life CHICAGO for life Chief Keef chop durk Reese Gino sad the whole Chicago what it do joe we living it up joy Chicago joy for life too fredo."
"Rest up easy love you brother," Travis Scott posted.
Disclaimer: No Business Standard Journalist was involved in creation of this content
You’ve reached your limit of {{free_limit}} free articles this month.
Subscribe now for unlimited access.
Already subscribed? Log in
Subscribe to read the full story →*Subscribe to Business Standard digital and get complimentary access to The New York Times
Smart Quarterly
₹900
3 Months
₹300/Month
SAVE 25%
Smart Essential
₹2,700
1 Year
₹225/Month
SAVE 46%
*Complimentary New York Times access for the 2nd year will be given after 12 months
Super Saver
₹3,900
2 Years
₹162/Month
Subscribe
Renews automatically, cancel anytime
Here’s what’s included in our digital subscription plans
Exclusive premium stories online
Over 30 premium stories daily, handpicked by our editors
Complimentary Access to The New York Times
News, Games, Cooking, Audio, Wirecutter & The Athletic
Business Standard Epaper
Digital replica of our daily newspaper — with options to read, save, and share
Curated Newsletters
Insights on markets, finance, politics, tech, and more delivered to your inbox
Market Analysis & Investment Insights
In-depth market analysis & insights with access to The Smart Investor
Archives
Repository of articles and publications dating back to 1997
Ad-free Reading
Uninterrupted reading experience with no advertisements
Seamless Access Across All Devices
Access Business Standard across devices — mobile, tablet, or PC, via web or app
SAVE 25%