In a statement, the ministry said the sanctions against Russia had put global stability at risk, a matter Moscow said it and the United States bear particular responsibility for.
"We have already shown that we are not going to leave hostile acts unanswered... And we obviously reserve the right to take retaliatory measures," it said.
The ministry also urged the US to "get rid of its illusions and understand that no threat or pressure will force Russia to change its policy or sacrifice its national interests".
But such collaboration will only be fruitful if "politicians in Washington stop looking at the world through their exclusively American prism," the statement added.
Trump reluctantly signed off on the sanctions behind closed doors earlier Wednesday, bowing to domestic pressure. The step puts efforts to improve ties with the Kremlin in severe jeopardy.
The US president's anger was obvious in a signing statement in which he called the legislation "significantly flawed.
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