Former world number one Sharapova, the 2006 US Open winner in her first Grand Slam since serving a 15-month doping ban, downed the 139th-ranked wildcard 7-5, 6-2 and moved into a fourth-round clash with Latvian 16th seed Anastasija Sevastova.
Five-time Grand Slam champion Sharapova, who tested positive for the blood booster meldonium at the 2016 Australian Open, reached the round of 16 for the 14th time in 15 Slams since the 2011 US Open.
The 30-year-old Russian broke Kenin with a forehand winner after 66 minutes to swipe the first set, exchanged early second-set breaks on double faults then broke again in the sixth and last games for the victory.
"She came out and had nothing to lose so I'm really glad I got through," Sharapova said.
Sharapova blasted eight aces and 38 winners with 33 unforced errors while Kenin hit only seven winners in the match.
"(The injury) played a quite significant part, and just being injured and not being able to keep that good form," Cilic said.
Cilic's exit ensured a first-time Slam finalist will come from his draw half, which now lacks a top-10 player and has only one Slam semi-finalist, American Sam Querrey, who made it in July at Wimbledon.
"Everyone is improving," Cilic said. "And you have a lot of youngsters coming up that are playing better."
The 18-year-old Israeli-born world number 69 advanced when Britain's Kyle Edmund retired with a neck injury with the Canadian leading 3-6, 6-3, 6-3, 1-0.
Not since 17-year-old Michael Chang in 1989 had a younger player cracked the fourth round in New York. No qualifier had reached the last 16 since Gilles Muller in 2008.
"I'm playing my second main draw Slam. It's huge," Shapovalov said. "It opens up the draw and helps players like myself have a chance."
Shapovalov will play for a quarter-final berth against Spanish 12th seed Pablo Carreno Busta, who ousted French qualifier Nicolas Mahut 6-3, 6-4, 6-3.
With US 10th seed John Isner being ousted 6-4, 6-3, 7-6 (7/5) by German 23rd seed Mischa Zverev, Carreno Busta became the top remaining seed in his half of the draw. Zverev gets US 17th seed Querrey next.
Italy's Paolo Lorenzi, 35, became the oldest player in the Open Era to reach a Grand Slam last 16 for the first time by defeating countryman Thomas Fabbiano 6-2, 6-4, 6-4.
Lorenzi next meets South African Kevin Anderson, who beat Croatian Borna Coric 6-4, 6-3, 6-2. Anderson has won all 43 of his US Open service games and saved all 14 break points he has faced.
===========================
Baby news from Florida turned heads as Serena Williams, a 23-time Grand Slam champion and six-time US Open winner, gave birth to a baby daughter.
She was pregnant in January when she beat older sister Venus Williams in the Australian Open final. US ninth seed Venus beat Greece's 95th-ranked Maria Sakkari 6-3, 6-4 and said she was "super-excited."
"To win in straight sets shows I'm playing some good tennis," Venus said.
Wimbledon champion Garbine Muguruza needed only 62 minutes to defeat Slovakian 31st seed Magdalena Rybarikova 6- 1, 6-1 and continue her best US Open run as well as take command of the fight for women's world number one.
"I'm taking every match as a final here," Muguruza said.
Awaiting Muguruza next is Czech 13th seed Petra Kvitova, the 2011 and 2014 Wimbledon champion who defeated French 18th seed Caroline Garcia 6-0, 6-4.
Disclaimer: No Business Standard Journalist was involved in creation of this content
You’ve reached your limit of {{free_limit}} free articles this month.
Subscribe now for unlimited access.
Already subscribed? Log in
Subscribe to read the full story →
Smart Quarterly
₹900
3 Months
₹300/Month
Smart Essential
₹2,700
1 Year
₹225/Month
Super Saver
₹3,900
2 Years
₹162/Month
Renews automatically, cancel anytime
Here’s what’s included in our digital subscription plans
Exclusive premium stories online
Over 30 premium stories daily, handpicked by our editors


Complimentary Access to The New York Times
News, Games, Cooking, Audio, Wirecutter & The Athletic
Business Standard Epaper
Digital replica of our daily newspaper — with options to read, save, and share


Curated Newsletters
Insights on markets, finance, politics, tech, and more delivered to your inbox
Market Analysis & Investment Insights
In-depth market analysis & insights with access to The Smart Investor


Archives
Repository of articles and publications dating back to 1997
Ad-free Reading
Uninterrupted reading experience with no advertisements


Seamless Access Across All Devices
Access Business Standard across devices — mobile, tablet, or PC, via web or app
