SRK last hosted hosted IIFA in 2005.
The award ceremony is returning to Macau for a second time this year after 2009.
The award show will see performances from Deepika Padukone, Madhuri Dixit and Abhishek Bachchan. Actor-director-choreographer Prabhudeva will also perform with Sridevi in a dance off.
IIFA 2013 will be held at the Venetian Macao, the official host destination partner and is supported by the Macau Government tourist office.