England, the European qualifying tournament runners-up, toyed with their South American rivals with 64 per cent ball possession and Chile were at the mercy of the rampaging Young Lions forwards several times.
England had as many as as 21 shots at the goal out of which nine were on target as the Group F match gradually turned into a one-sided one.
Sancho struck in the 51st and 60th minutes, while Callum Hudson Odoi (5th) and Angel Gomes (81st) were the other scorers.
To make matters worse for Chile, who had watched blockbuster Bollywood movie 'Chak De! India' as part of their build-up, they were reduced to 10 men in the 79th minute when goalkeeper Julio Borquez was shown a straight read card for a harsh foul on an opposition player.
For the sizeable crowd at the brand new Salt Lake Stadium, it was a treat to watch a quality England team scoring goals at will.
Sancho showed his class with his deft footwork. He and striker Rhian Brewster were a constant threat for Chile from the left side.
Sancho, who recently joined Borussia Dortmund from Manchester City, weaved his way through the Chile box from the left and sent a brilliant pass for Callum Hudson Odoi who calmly sent the ball past the goalkeeper to give England a 1-0 lead in the fifth minute.
England could have doubled their lead in the 19th minute but Brewster missed a sitter from a handshaking distance. After playing a one-two with Odoi at the edge of the box, Philip Foden curled a cross towards an unmarked Brewster, but the striker's shot went wide.
The Young Lions did even better in the second half, pumping in three more goals.
If the first goal was an assist from Sancho, the star left winger, who will play only upto the group stage, himself entered his name in the score sheet in the 51st minute.
Chile goalkeeper Borquez, who has had a fine tournament in the South American qualifiers, could not hold onto a low cross from the right and Sancho calmly pushed the ball home.
Cooper brought in Gomes, who recently made a Premier League debut in the 67th minute in place of Odoi, and drama followed.
Chile keeper Borquez ended his nightmarish day when he was red-carded in the 79th minute for a harsh challenge on Brewster. Chile, who had already made three substitutions, were forced to ask midfielder Branco Provoste to take charge under the goalpost.
Disclaimer: No Business Standard Journalist was involved in creation of this content
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