Local Internet providers restored access to blocked websites that also included the Russian social networks Odnoklassniki and VKontakte, as well as popular independent news agency Asia Plus, following pressure from the United States.
A block on the Tajik service of Radio Free Europe, Radio Ozodi, was not lifted however.
Tajikistan had prevented access to the websites on May 28, a day after 40-year-old Colonel Gulmurod Halimov appeared in footage blasting the country's anti-Islamic policies and swearing loyalty to the radical group.
The latest blocks were among the most wide-ranging in recent years, indicating the government is rattled by Colonel Halimov's shock defection.
The American Embassy in Dushanbe last week released a statement over the blocks, including on Ozodi, which receives US government funding, saying: "We urge the government of Tajikistan to lift any restrictions on Facebook, Radio Ozodi, and other Internet news and social media sites."
Halimov is the highest profile recruit to IS from formerly communist Central Asia, an economically depressed region which borders Afghanistan and shares close ties with Russia and China.
In a 12-minute clip featuring the logo of the Furat media collective believed to be controlled by Islamic State, Halimov called Tajikistan's leadership "dogs" and Americans "pigs".
"We are coming for you, Inshallah! (God willing)" he warned the Tajik government.
Halimov was placed on the Interpol wanted list last week and Tajikistan has charged him with treason and involvement in a criminal group along with other crimes.
Tajikistan's Interior Minister Ramazon Rahimzoda on Friday said that at least 412 Tajik citizens have joined Islamic State since the outbreak of war in Syria, 71 of whom have died.