The assailants burst into a home in the village of Nueva Frontera in the northwest of the country, police spokesman Leonel Sauceda said, with two others left wounded in the brutal attack.
Honduras, plagued by feuding street gangs and drug trafficking that helps feed the US market, is rated one of the world's most violent countries.
In the first massacre this week, suspected gang members in the northern city of Choloma killed eight bus drivers Tuesday for refusing to pay extortion money that gangs charge businesses and refer to as a "war tax."
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