Notably, this is only the fourth time the US has imposed sanctions on a sitting head of state.
"Sunday's illegitimate elections confirm that Maduro is a dictator who disregards the will of the Venezuelan people. By sanctioning Maduro, the United States makes clear our opposition to the policies of his regime and our support for the people of Venezuela who seek to return their country to a full and prosperous democracy," US Treasury Secretary Steven T Mnuchin said yesterday.
At a White House news conference, the National Security Adviser, Lt Gen H R McMaster said: "Since Trump's inauguration, the administration has called on Maduro regime to respect Venezuela's constitution, respect the role and authorities of the constitutionally established National Assembly, hold free and fair elections, address the humanitarian needs of the Venezuelan people, release political prisoners and stop oppressing its great people."
"The regime has refused to heed this call and its recent actions culminating in yesterday's outrageous seizure of absolute power through the sham election of the National Constituent Assembly represent a very serious blow to democracy in our hemisphere. Maduro is not just a bad leader, he is now a dictator," McMaster said.
The US is broadening its effort to address the ongoing assault on Venezuela's democratic institutions by the Maduro regime.
"As a result of today's sanctions, all assets of Maduro subject to US jurisdiction are frozen and US persons are prohibited from dealing with him," Mnuchin told reporters at the White House news conference.
"The National Constituent Assembly aspires illegitimately to usurp the constitutional role of democratically elected National Assembly, rewrite the constitution and impose an authoritarian regime on the people," he said.
"As such, it represents a rupture in Venezuela's constitutional and Democratic order. By sanctioning Maduro, the United States makes clear our opposition to the policies of his regime and the support for the people of Venezuela, who strive to return their country to a full and prosperous democracy," said the Treasury Secretary.
"We will continue to monitor the situation and consider additional sanctions," he added.
According to McMaster, Trump has prioritised his concern for the Venezuelan people and therefore he is only considering those options which would directly benefit them.
Maduro was elected as the president of Venezuela on April 14, 2013, following the death of former President Hugo Chavez.
Maduro held previous roles in the Venezuelan government, including as Executive Vice President and Minister of Foreign Affairs.
Washington has been a longstanding opponent of Maduro's government and of his predecessor but yesterday's statement marks the first time that a senior official had publicly branded him a dictator.
Any member of the opposition or critic of the regime risks being detained, imprisoned, assaulted, tortured, and assassinated, the US alleged.
Top Republican Senator Marco Rubio termed the imposition of sanctions on Maduro as "warranted".
"However, I remain confident the president will keep his clear commitment to impose economic sanctions on the regime if they convene the illegitimate Constituent Assembly," Rubio said.
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