The closed-door session is tasked with ruling whether the outbreak constitutes what is known in WHO-speak as a "public health emergency of international concern".
Taking the form of a telephone conference between senior WHO officials, representatives of affected countries, and experts from around the globe, the meeting is not expected to made its decision public until Friday.
To date, the WHO has not issued global-level recommendations -- such as travel and trade restrictions -- related to the outbreak which began in Guinea and has spread to Liberia, Sierra Leone and Nigeria.
The UN agency this year held such meetings on polio and last year on the mysterious Middle East Respiratory Syndrome.
But before that, the last emergency meeting had been during the 2009 H1N1 influenza outbreak.
Since breaking out earlier this year, the Ebola epidemic in west Africa has claimed 887 lives and infected more than 1,603 people.
Most of the deaths have been in Guinea, but the scale of the epidemic has slowed there, while intensifying in neighbouring Liberia and Sierra Leone.
Ebola, a form of haemorrhagic fever for which there is no vaccine, causes severe muscular pain, fever, headaches and, in the worst cases, unstoppable bleeding.
It is believed to be carried by animals hunted for meat, and spreads among humans via bodily fluids.
It has killed around two-thirds of those it has infected since its emergence in 1976, with two outbreaks registering fatality rates approaching 90 percent.
The death rate in the current outbreak is around 55 percent.
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