It would be a long struggle against extremism, but "we are heading in the right direction", Kerry said at the World Economic Forum (WEF) here.
He was clear that the US will strengthen its fight against corruption, which is used by extremist groups as a recruitment tool.
"The fact is there is nothing, absolutely nothing, more demoralising and disempowering to any citizen of any nation than the belief that the system is rigged against them...," he said, adding that corruption complicates every single security, diplomatic and social initiative.
"The world is not witnessing global gridlock. We are not frozen in a nightmare we cannot wake up from... If we stay serious and work in good faith, we can make progress," Kerry said.
Calling for providing opportunities to the youth, Kerry said there are 700 million people under 30 years and all of them are seeking opportunity, dignity and respect and are aware of what they don't have in a world where everyone is connected 24/7.
According to him, a coalition of countries has come together to fight Da'esh (ISIS) and praised the military successes achieved by the joint action of coalition air power and local ground forces.
"In the end, mark my words, Da'esh (ISIS) will be defeated, and the progress we have made towards that goal has been remarkable," Kerry said.
Da'esh has already lost over 30 per cent of the territory it once held and much of its financing, the secretary added.
About the conflict in Syria, Kerry said key steps have been taken to resolve it and all the countries involved have agreed on a list of principles for a post-war Syria.
"Nothing would do more to end the threat of Da'esh than to negotiate an end to the war in Syria," the secretary said.
