"My understanding is that bishops and pastors are there to pray for those who go wrong, not to enter into political lives," Zuma told journalists after the Anglican archbishop emeritus last month questioned the calibre of the country's leaders.
Known as South Africa's moral compass, Tutu has been very critical of the ANC government's graft scandals and poor governance.
A few weeks ago he reaffirmed that the ruling party would not get his ballot in the May 7 elections.
Zuma's government has limped from one scandal to another, the most prominent being USD 23 million in state-paid security upgrades at his private rural homestead.
This has prompted a group of ANC stalwarts to call on voters to spoil their ballot -- a campaign which Tutu supported.
But Zuma disapproved of the measure.
"For pastors to say don't vote... I think to me that is a problem. That is entering into a political thing," he said.
Other political parties also often invoke religion in their support.
Relations between the "Arch" and the ANC have been prickly in recent years, but the party has carefully worded its responses to the often-public diatribes of a popular figure.
"I respect pastors, I respect bishops. That is his views, it is his own views, and he talks to people," Zuma said today.
