No. 21 John Isner went through 6-4, 6-1, 6-3 against Elliot Benchetrit and the big-serving American next meets qualifier Sebastian Korda, whose father, Petr, won the 1998 Australian Open and was the runner-up here in 1992. The 20-year-old Korda beat Andreas Seppi of Italy 6-2, 4-6, 6-3, 6-3.
No. 27 Taylor Fritz relinquished a two-set lead but the American held firm to win 7-5, 7-6 (2), 1-6, 2-6, 6-3 against Tomas Machac.
No. 17 Anett Kontaveit lost 6-4, 3-6, 6-4 to Frenchwoman Caroline Garcia, but No. 20 Maria Sakkari and No. 27 Ekaterina Alexandrova both advanced.
In the pick of Sunday's later matches, three-time Grand Slam winners Andy Murray and Stan Wawrinka were playing on Chatrier in the 21st meeting between the veterans. Wawrinka won here in 2015 and Murray lost the final to Novak Djokovic the following year.