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Taking paracetamol during pregnancy might increase the offspring's chances of developing neurodevelopmental disorders, including autism and attention deficit hyperactivity disorder, according to a study. Available over-the-counter, paracetamol -- also known as 'acetaminophen' -- is considered safe for managing headache, fever, and pain during pregnancy. Researchers, including those at the Icahn School of Medicine at Mount Sinai, US, analysed 46 previously published studies involving over a lakh participants across multiple countries. Findings published in the journal BioMed Central show that "higher-quality studies are more likely to show a link between prenatal acetaminophen exposure and increased risks of autism and ADHD," said author Diddier Prada, assistant professor of population health science and policy, environmental medicine and climate science, at the Icahn School of Medicine at Mount Sinai. "Given the widespread use of this medication, even a small increase in risk could
Paracetamol, a common over-the-counter medication, may increase the risk of gastrointestinal, heart- and kidney-related complications among adults aged 65 and above, a new study has found. Taken commonly for treating mild-to-moderate fever, paracetamol is also the first drug recommended for treating osteoarthritis -- a chronic condition causing pain, stiffness and swelling in the joints due to wear-and-tear -- as it is considered effective, relatively safe and accessible. However, some studies have provided evidence to contest the effectiveness of paracetamol in relieving pain while others have shown increased risks of gastrointestinal side effects, such as ulcers and bleeding, from prolonged use. The latest study, conducted by researchers from the University of Nottingham, UK, found that paracetamol use was linked to a 24 per cent and 36 per cent increase in risk of peptic ulcer bleeding (bleeding due to ulcer in the digestive tract) and lower gastrointestinal bleeding, ...