Unidentified men riding a motorcycle fired indiscriminately in Pasni Bazar, 720 km southwest of provincial capital Quetta.
One person was killed and another sustained severe injuries. The wounded person died while being taken to hospital, police said.
Another person was killed in firing in Panjgur Bazar, Dawn News reported.
No group claimed responsibility for both attacks.
Balochistan has rocked by sectarian violence and attacks by Baloch separatists and militant groups. Scores of people have lost their lives in suicide bombings and targeted killings.