"Burundi faces a malaria epidemic," Josiane Nijimbere said yesterday, commenting on a World Health Organisation (WHO) report.
From January 1 to March 10 this year, 1.8 million infections were registered in Burundi, according to the WHO.
According to Nijimbere, the latest figures constitute a 17 per cent increase from the same period last year.
"Some 700 deaths" have been registered since January, the minister added.
In 2016, an estimated 8.2 million people were infected and 3,000 people died in mountainous Burundi, which is home to around 11 million people.
Nijimbere put the cost of fighting malaria at USD 31 million (29 million euros), as she appealed for donations to help fight the disease.
She attributed the rise in infections to climate change, increased marshland for rice-growing and the population's misuse of mosquito nets.
Burundi has been plunged into chaos since President Pierre Nkurunziza's controversial decision in April 2015 to run for a third term.
Hundreds of people have been killed and hundreds of thousands of others have fled the country.
The crisis also led to a 54 per cent cut to the government's health budget in 2016 from the previous year.
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