Jenkins replaces Barclays former chief executive officer Bob Diamond who resigned following the scandal.
"Barclays PLC and Barclays Bank PLC announce that Antony Jenkins has been appointed as a Director and as Group Chief Executive of Barclays with immediate effect," Barclays group said in a statement.
Jenkins currently leads Barclays Retail and Business Banking (RBB) business. He has been a member of the Group Executive Committee of Barclays since 2009.
Barclays has made "serious mistakes in recent years and clearly failed to keep pace with our stakeholders' expectations", Jenkins said.
Last month, the British bank was slapped with 290 million pound (USD 451 million) fine by the US and the UK authorities to settle the charges of manipulating global benchmark lending rates like Libor, and Euribor, which influence many other interest rates.
"We have an obligation to all of those stakeholders
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