In a gloomy results statement, GSK said it now expected its earnings per share - a key measure of performance - to be "broadly flat" this year. That compared with the previous forecast for growth of 4.0-8.0 per cent.
Net profit, or profit after tax, dived 37 per cent to USD 1.11 billion in the three months to June 30, down from 1.045 billion Pounds in the same period of last year, GSK added.
Stripping out the impact of currency fluctuations, revenues fell four per cent.
GSK said its performance was hit by "continued increased competition in US respiratory market and generic competition to Lovaza", which is the group's key fish-oil heart drug.
China's corruption probe into its staff continued to weigh on sales, while the group repeated it was fully cooperating with authorities.
"China, acting through various government agencies, continues its investigation into alleged crimes and violations of law by GSK's China operations," GSK said in today's statement.
GSK last year admitted senior employees appeared to have breached Chinese law, after Beijing authorities alleged staff had bribed government officials, pharmaceutical industry groups, hospitals and doctors to promote sales.
In May, Britain's Serious Fraud Office launched a criminal investigation into the group's commercial practices.
GSK's share price fell 3.50 per cent to 1,500.5 pence, making it the biggest loser in London's benchmark FTSE 100 index, which was up 0.15 per cent to 6,805.32 points in afternoon trade.
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