In a speech in the Aegean city of Izmir, Erdogan described Europe as a "sick man", using the jibe that nineteenth century European politicians used to describe the decaying Ottoman Empire.
He once again threatened after the April 16 referendum to sign into law the reinstatement of the death penalty - if it was passed by parliament - a move that would automatically end the European Union membership bid.
He said that Turks living in Europe were "oppressed" and "humiliated": "God willing, our people will bring them (Europe) to account," he said.
"They said a century ago that we were the 'sick man'. Now they are the 'sick man'. Europe is collapsing," he added, claiming the European economy weakened every year.
The EU is facing the gravest crisis in its six-decade history after last year's British vote to leave the bloc, while populist and eurosceptic movements have gained ground across the continent.
The president has raised hackles in Europe over recent weeks by claiming some EU states were behaving like the Nazis by preventing his ministers from holding pre-election rallies.
While the 'No' campaign has struggled to make its voice heard as the 'Yes' campaign dominates the airwaves, analysts believe the outcome is still too close to call as the race enters the last week of campaigning.
Today marked the last day of expatriate voting in the referendum which is expected to be crucial to the outcome with some three million expatriate voters registered, almost half of them in Germany.
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