Researchers investigated how psychological factors might influence risk for chronic disease, using data from an ongoing study on cardiovascular disease risk factors in participants living in six US cities.
More than 6,700 adults (ages 45-84; 53 per cent women) completed questionnaires assessing chronic stress, depressive symptoms, anger and hostility over two years.
Participants were 38.5 per cent white, 27.8 per cent African-American, 11.8 per cent Chinese and 21.9 per cent Hispanic. All were free of cardiovascular disease at the start of the study.
A TIA is a stroke caused by a temporary blockage of blood flow to the brain.
Compared to people with the lowest psychological scores, those with highest scores were 86 per cent more likely to have a stroke or TIA for high depressive symptoms.
They were 59 per cent more likely to have a stroke or TIA for the highest chronic stress scores and more than twice as likely to have a stroke or TIA for the highest hostility scores.
No significant increased risk was linked to anger.
These associations noted in the study were significant even when researchers accounted for age, race, sex, health behaviours and other known risk factors of stroke.
Researchers measured chronic stress in five domains: personal health problems, health problems of others close to the participant, job or ability to work, relationships and finances.
Hostility, which is a negative way of viewing the world, was measured by assessing a person's cynical expectations of other people's motives.
The research was published in the American Heart Association journal Stroke.
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