Lad was unconquered on 94 while Patil, playing only his second game of the season, was not out on 85 as the sixth- wicket duo put the visiting team attack to the sword with an unfinished partnership of 175 in just over two and a half hours after combining forces midway through the second session of play at the Wankhede Stadium.
It was a tricky time as another wicket would have sent Mumbai crashing for a low total in the first innings after they had chosen to bat, but the two youngsters showed splendid fighting spirit to pull the 40-time champions out of trouble with aggressive stroke-play.
Karnataka also did not take all their chances as Lad was twice let off, when on 13 in a team score of 148 for 5 by Manish Pandey off captain Vinay Kumar and then on 55 by R Samarth off Abhimanyu Mithun.
His partner Patil was marginally ahead of him at the tea score of 230 for 5 after a brisk beginning but then played a bit more sedately to remain unconquered at the end after facing 129 balls and striking two sixes and 11 fours.
For Karnataka, Vinay Kumar bagged the first two wickets - Mangela and Iyer, to end with decent figures of 2 for 65. Off- spinner Udit Patel also picked up two wickets in the space of seven balls when he sent back experienced batsmen Nayar and Yadav to finish the day with 2 for 68.
Scores: Mumbai 342 for 5 (A Tare 72, A Nayar 36, S Lad batting 94, N Patil batting 85; Vinay Kumar 2 for 65, Udit Patel 2 for 68) v Karnataka.
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