The study by the University of Waterloo monitored the smoking behaviours of 72 adults as they switched to three types of cigarettes with markedly reduced nicotine levels.
Unlike when smokers switch between conventional cigarette brands - all of which have very similar levels of nicotine content - the study found no change in participants' puffing behaviour, number of cigarettes consumed or levels of toxic chemicals in their systems.
The landmark findings may ease concerns that smokers would increase their consumption of cigarettes or puff harder if governments reduced nicotine levels to negligible amounts.
"The smokers were unable or unwilling to compensate when there was markedly less nicotine in the cigarette and when the experience of smoking is far less rewarding," said Hammond.
The cigarettes used in the study had a nicotine content of 8.9, 8.4 and 0.6 mg, respectively, as opposed to an average of 12 mg in a regular cigarette.
"Overall, the impact of a less-addictive cigarette on reducing smoking uptake and cancer prevention is potentially massive," Hammond said.
The study was published in the journal Cancer Epidemiology.
